Gingerenone A
CAS No. 128700-97-0
Gingerenone A( AS-HK014 | AS HK014 | ASHK014 | Gingerenone A | Gingerenone-A )
Catalog No. M11170 CAS No. 128700-97-0
A dual inhibitor of JAK2 and S6K1 pathways, selectively kills cancer cells while exhibiting minimal toxicity toward normal cells.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 100MG | Get Quote | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product NameGingerenone A
-
NoteResearch use only, not for human use.
-
Brief DescriptionA dual inhibitor of JAK2 and S6K1 pathways, selectively kills cancer cells while exhibiting minimal toxicity toward normal cells.
-
DescriptionA dual inhibitor of JAK2 and S6K1 pathways, selectively kills cancer cells while exhibiting minimal toxicity toward normal cells; induces apoptosis in cancer cells and suppresses tumor growth in vivo associated with relative phosphorylation levels of JAK2 and S6K1; suppresses obesity and adipose tissue inflammation in high-fat diet-fed mice.
-
In Vitro——
-
In Vivo——
-
SynonymsAS-HK014 | AS HK014 | ASHK014 | Gingerenone A | Gingerenone-A
-
PathwayAngiogenesis
-
TargetJAK
-
RecptorJAK
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number128700-97-0
-
Formula Weight356.418
-
Molecular FormulaC21H24O5
-
Purity>98% (HPLC)
-
SolubilityIn Vitro:?DMSO : 100 mg/mL (280.58 mM)
-
SMILESO=C(/C=C/CCC1=CC=C(O)C(OC)=C1)CCC2=CC=C(O)C(OC)=C2
-
Chemical Name4-Hepten-3-one, 1,7-bis(4-hydroxy-3-methoxyphenyl)-, (E)-
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. Byun S, et al. J Biol Chem. 2015 Sep 25;290(39):23553-62.
2. Kim HJ, et al. J Cell Biochem. 2018 Jan;119(1):260-268.
3. Suk S, et al. Mol Nutr Food Res. 2017 Oct;61(10).
molnova catalog
related products
-
Decernotinib
Decernotinib (VX-509, VRT-831509) is a potent, selective, orally available JAK3 inhibitor with Ki of 2.5 nM and cellular IC50 of 50-170 nM.
-
Londamocitinib
Londamocitinib (JAK1-IN-7) is a selective and potent JAK1 inhibitor with anti-inflammatory activity.
-
AG-490
AG-490 (Tyrphostin AG 490) is a multi-targeted tyrphostin family of tyrosine kinase inhibitor.
Cart
sales@molnova.com